How to treat biotin-deficient conditions in children?
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PATENT: |
2795624 |
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INVENTION: |
Composition for the treatment of biotin-deficient conditions in children, as well as a method of treatment using such a composition |
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INNVENTOR(S): |
Kruglyakov Pyotr Vladimirovich, Lepeshkin Artem Ilyich |
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PATENTEE: |
PROMIX Limited Liability Company |
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PURPOSE: |
For the treatment of biotin-deficient conditions in children, including children aged under one year |
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INNOVATION: |
Biotinidase deficiency is a hereditary autosomal recessive disease from the group of organic acidurias, caused by a biotin-deficient condition. The disease is caused by a profound or partial absence of the enzyme biotinidase and is characterized by a wide range of clinical manifestations, which include neurological symptoms, skin manifestations, changes in the organs of vision and hearing, immune disorders. The average age at the disease onset is 3-6 months, in rare cases it manifests itself after 10 years. Early diagnosis is crucial, since early start of biotin treatment in the neonatal period provides an opportunity to prevent the formation of severe clinical manifestations. The use of specific biotin therapy in this pathology leads to the replenishment of biotin and the elimination of symptoms of the disease. To date, there is not a single composition that contains a therapeutic dose of biotin and is suitable for children, including children aged under one year, due to the fact that the additives contain components that are unacceptable for children. The inventors have developed a safe and effective solution for the treatment of biotin-deficient conditions for children aged under one year and older. The product is highly soluble, which allows it to be added to breast milk substitutes and to complementary foods. The composition contains biotin, vitamins B1, B2, B3, B5, B6, B9 and a filler, which is a mixture of dextrose and maltodextrin in a certain ratio. |
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SCOPE OF |
The invention relates to the field of medicine |
